Pharmaceutical solutions for the industry

Pharmaceutical

Polygel Global

Our Pharmaceutical Solutions:

PUREti TIPT is used in the manufacturing process of many prazole-class drugs (such as pantoprazole, omeprazole, lansoprazole, rabeprazole etc.), but not as an ingredient in the final drug formulation.

TIPT is often used as a catalyst or reagent in organic synthesis, especially in enolate formation and condensation reactions.

In prazole synthesis, it’s involved in steps like:

  • Catalyzing cyclization reactions.
  • Promoting selective oxidation or rearrangement.
  • Acting as a mild Lewis acid to enable specific bond formations.

The titanium species is removed during purification and does not remain in the API (active pharmaceutical ingredient) in any significant quantity.  It’s a process chemical, similar to how palladium catalysts are used in drug synthesis but aren’t part of the tablet/capsule itself.